Pharmaceutical Science & Technology

Plant-Derived Anticancer Drugs in the OMICS Era
Biosynthesis, Functions, and Applications

Editor: Deepu Pandita
Anu Pandita

Plant-Derived Anticancer Drugs in the OMICS Era

Now on Press
Pub Date: Forthcoming October 2023
Hardback Price: see ordering info
Hard ISBN: 9781774912652
E-Book ISBN: 9781003377412
Pages: 322pp w/ index
Binding Type: Hardback/ e-book
Notes: 22 color and 22 b/w illustrations

The current anti-cancer synthetic medicines are inefficient and unsafe. The plants-based lead molecules such as taxol, camptothecin, podophyllotoxins, vinblastine, vincristine, homoharringtonine and numerous other anticancer compounds from Nature’s arsenal are potentially safe and powerful alternative means that effectively fight against cancer.

The volume looks at a variety of medicinal plants and approaches that have beneficial results against cancer. Topics include Unani approaches of anticancer plants, genetic engineering and CRISPR/CAS-mediated editing to enhance anticancer potential, computational approaches used in anticancer plants, and more. The volume also examines the metabolomics of plants that give them anti-cancer properties.

This volume, Plant-Derived Anticancer Drugs in the OMICS Era: Biosynthesis, Functions, and Applications, will be valuable to cancer researchers and drug developers among others.

CONTENTS:
Preface

1. Evaluation of Extracts from Curcumalonga and Zingiber officinale as Growth Inhibitors of HeLa and HuH-7 Cell Lines
Jordi Orlando González-Osuna, Alberto Barbabosa-Pliego, Esvieta Tenorio-Borroto, Salvador Chavez-Salinas, María Uxua Alonso-Fresan, Jose Maria Eloy Contreras-Ortiz, Juan Carlos Vazquez-Chagoyan, Luis German Lopez-Valdez, Cesar Reyes, Braulio Edgar Herrera-Cabrera, Fabiola Zaragoza-Martinez, Gonzalo Guillermo Lucho-Constantino, and Hebert Jair Barrales-Cureno

2. Role of Herbal Medicines in Liver Cancer
S. Nizamudeen, Yumna Baqi, and Sarafraz Arqum Shah

3. Unani Approaches of Anticancer Plants Against Cancer
Sana Nafees and Huda Nafees

4. Exploration of Anticancer Medicinal Plants of the Northern Hemisphere
Younis Ahmad Hajam, Aishwarya Sharma, Javid Ahmad Malik, Rajesh Kumar, and Raksha Rani

5. Genetic Engineering of Plants for Enhanced Anticancer Potential
Bushra Hafeez Kiani

6. Genetic Engineering of Plants of Enhancing Secondary Metabolites with Anti-Cancerous Properties
Nilanjana Das and Aryadeep Roychoudhury

7. Genomics of Plants with Anticancer Properties: Breaking New Ground in Cancer Therapy
Mubasshira Mohammed Mazhar Ul Haque, Lekha Bhagtaney, and Priya Sundarrajan

8. Metabolomics of Anti-Cancer Plants
S. Ruth Assumi, Khanmi Kasomva, and Pooja Bhadrecha

9. Computational Approaches Used in Anticancer Plants
Fulden Ulucan-Karnak, Zeynep Yilmaz-Sercinoglu, Onur Sercinoglu, and Ahmad Ali

10. CRISPR/CAS-Mediated Editing of Anticancer Plants
Muhammad Shan, Zulqurnain Khan, and Muhammad Arslan Akhtar

11. Zinc Finger Nuclease (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs): Based Genome Editing in Enhancement of Anticancer Activity of Plants
Pooja Saraswat, Ambika Chaturvedi, and Rajiv Ranjan

Index


About the Authors / Editors:
Editor: Deepu Pandita
Senior Lecturer, Government Department of School Education, Jammu, Union Territory of Jammu and Kashmir, India

Deepu Pandita is working as a Senior Lecturer in the Government Department of School Education, Jammu, Union Territory of Jammu and Kashmir, India. Deepu Pandita has more than 19 years of teaching experience and has a master’s in Botany from the University of Kashmir, Jammu and Kashmir, India, and a master’s in Philosophy in Biotechnology from the University of Jammu, Jammu and Kashmir, India. Deepu Pandita has a number of international and national courses to her credit. Deepu Pandita has qualified for fellowships, such as JRF-NET and SRF from the Council of Scientific and Industrial Research (CSIR), New Delhi India; Biotechnology Fellowship, Government Department of Science and Technology, Jammu & Kashmir, India; and IASC-INSA-NASI Summer Research Teacher Fellowship, India. Deepu Pandita has presented her research work at both national and international conferences and was awarded Best Oral Presentation Award at an International Conference on Biotechnology for Better Tomorrow, a Women Researcher Award, and a Research Excellence Award from two professional associations in India. Deepu Pandita is a life member of various science societies. Deepu Pandita acts as a reviewer (18 journals), associate editor, and editor of a number of international journals. Deepu Pandita has published a number of editorials, book chapters (Springer, CRC, and Elsevier), reviews, and research articles in various journals of national and international repute.

Anu Pandita
Dietician, Vatsalya Clinic, New Delhi, India

Anu Pandita is working as a Dietician at Vatsalya Clinic, E-5/11, Krishna Nagar, New Delhi, India. Previously she worked as a lecturer at Bee Enn College of Nursing, Talab Tillo, Jammu, India, and Dietician at Ahinsa Dham Bhagwan Mahavir Charitable Health Centre, New Delhi, India. Anu Pandita has done her MSc internship and a course in the Dietetics Department of PGI, Chandigarh, India. Anu Pandita conducted a case study at the Pediatric Gastroenterology Ward at Nehru Hospital, PGI, Chandigarh, India, on a patient suffering from chronic liver disease. She has done a Certificate in Food & Nutrition as well. She has a number of trainings, refresher courses, and workshops to her credit. Anu Pandita is a life-time member of the Indian Dietetic Association and Indian Science Congress Association, Kolkata, India. Anu Pandita has published for book chapters in Springer journals and a number of reviews and research articles in various journals of national and international repute. Anu Pandita has presented her research work at both the national and international conferences.




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