Pharmaceutical Science & Technology

Pharmaceutical Microemulsions for Parenteral Delivery
From Bench to Bedside

Editors: Vivek P. Chavda, MPharm
Vandana B. Patravale, PhD

Pharmaceutical Microemulsions for Parenteral Delivery

In production
Pub Date: Forthcoming Spring 2025
Hardback Price: $240 US | £180 UK
Hard ISBN: 9781774916605
E-Book ISBN: 9781003499817
Pages: Est. 346pp w/index
Binding Type: Hardback / ebook
Notes: 7 color and 9 b/w illustrations


Reviews
“Covers important aspects of parenteral microemulsions, ranging from formulation to characterization, highlighting parenteral pharmaceutical applications, including clinical and regulatory aspects–both prerequisites for successful product developments for the benefit of patients. We are confident this book will stimulate further research in parenteral microemulsions.”
—From the Foreword by Rainer H. Müller, PharmaSol GmbH Berlin, Germany, and Cornelia M. Keck, Phillips University of Marburg, Germany

Parenteral delivery of hydrophobic drugs is a challenging task. Constant research on exploiting newer approaches to make the delivery of pharmaceuticals by nondigestive tracts effective yet safe and cost effective continues. Microemulsion is one such approach that has been employed in recent years for parenteral delivery. This new book, Pharmaceutical Microemulsions for Parenteral Delivery: From Bench to Bedside, provides systematic information regarding the preformulation of drugs, formulation using quality by design (QbD) principles, and characterization of parenteral microemulsions for drug delivery.

The book explores specific aspects of microemulsions such as the role of surfactants and cosurfactants in formulation, clinical aspects of parenteral microemulsion, regulatory perspectives and patents, as well as future challenges in this field of research. It covers the QbD paradigm for formulation optimizations using different software systems. It also covers the regulatory expectations and safety issues at various stages of the development pharmaceutical microemulsions. The book details large-scale manufacturing aspects as well as presents an overview of the patent landscape for parenteral use of microemulsions.

Serving as a reference guide for the development of parenteral microemulsion-based formulations, this volume will be an important source of know-how for investigators wishing to work in this area, be it from academia or industry.

CONTENTS:
Foreword by Rainer H. Müller and Cornelia M. Keck

Preface

1. Impact of Parenteral Microemulsion on Healthcare Therapeutics: A Bird’s Eye View
Amol D. Gholap, Harita Desai, and Lalitkumar K. Vora

2. Preformulation Studies for Microemulsion Formulation
Mangal Nagarsenker, Saurabh Katawale, Harshali Dhaygude, Vivek Dhawan, and Abhijit A. Date

3. Role of Surfactants and Co-Surfactants for Formulation
Namdev Dhas, Kumar Nishchaya, Chandrakant Pardeshi, Prabhakar Panzade, Vipul Patel, Ritu Kudarha, Swarali Kadam, and Srinivas Mutalik

4. Application of Quality by Design in Microemulsions
Manju Misra, Mohammadhassan Harsoliya, Rutvi Shah, and Janki Kakkad

5. Parenteral Self-Emulsifying Drug Delivery
Siva Nageswara Rao Gajula, Moinuddin Soniwala, Sunny Shah, Shilpa Daware, Lakshmi Vineela Nalla, and Vivek Chavda

6. Characterization of Parenteral Microemulsions
Katherine Bang, Sunil Prabhu, and Preshita Desai

7. Clinical Aspects of Parenteral Microemulsion
Pankti C. Balar, Dixa Vaghela, Lajja Patel, Tejal Mehta, and Pragna Shelat

8. Pharmaceutical Applications of Microemulsion for Parenteral Delivery
Chukwuebuka Emmanuel Umeyor, Satyam Gupta, Abhishek Rai, Vivek P. Chavda, and Vandana B. Patravale

9. Regulatory Perspective and Patents for Parenteral Microemulsion Formulations
Saikat Ghosh, Amit Dabke, Ami Patel, Priyansh Pandya, and Krutika K. Sawant

10. Future Challenges for Parenteral Microemulsion
Vivek P Chavda, Kajal Bhaviskar, and Dixa Vaghela

Index


About the Authors / Editors:
Editors: Vivek P. Chavda, MPharm
Assistant Professor, Department of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India

Vivek P. Chavda, MPharm, is currently working as an Assistant Professor in the Department of Pharmaceutics and Pharmaceutical Technology at the L. M. College of Pharmacy, Ahmedabad, Gujarat, India. Before joining academics, he worked in the Biologics industry for almost eight years in research and development, with two successful regulatory filings at Lupin Biotech (Pune) and Dr. Reddy’s Laboratory (Hyderabad). He has published over 250 national and international journal papers, 33 book chapters, with 10 book chapters in progress, nine patents in the pipeline, and numerous newsletter articles to his credit. His research interests include the development of biologics processes and formulations, medical device development, nano-diagnostics, long-acting parenteral formulations, and nano-vaccines. He is serving as an editorial board member for various Scopus-indexed, peer-reviewed journals and was listed among the top 2% of scientists in the world by Stanford University and Elsevier in 2023 and 2024. He is a BPharm and MPharm Gold Medalist at Gujarat Technological University.

Vandana B. Patravale, PhD
Professor of Pharmaceutics, Institute of Chemical Technology, Mumbai, India

Vandana B. Patravale, PhD, is a Professor of Pharmaceutics at the Institute of Chemical Technology, Mumbai, India. Her research interests include development of nano-carriers with a major emphasis on infectious diseases, cancer and neurodegenerative disorders, medical device development, nano-diagnostics, and nano-vaccines. She has over 200 refereed publications, two books, and over 25 book chapters to her credit. She holds 31 granted patents and has 14 patents in progress and two trademark registries to her credit. She is the Vice President of the Controlled Release Society (Indian Chapter) and the National Convenor of the Women‘s Forum of the Association of Pharmaceutical Teachers of India. She is actively involved in the pharmaceutical industry and has transferred more than 20 technologies to various industries, including technology on drug-eluting stents, which are being marketed in more than 60 countries.




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