Medicine & Health Sciences

Obesity Epidemiology, Pathogenesis, and Treatment
A Multidisciplinary Approach

Editor: Rexford S. Ahima, MD, PhD

Obesity Epidemiology, Pathogenesis, and Treatment

Published. Available now.
Pub Date: January 2014
Hardback Price: see ordering info
Hard ISBN: 9781771880084
Paperback ISBN: 978-1-77463-330-4
E-Book ISBN: 9781482240795
Pages: 382pp
Binding Type: hardbound / ebook / paperback

Now Available in Paperback


This title includes a number of Open Access chapters.

The book provides a comprehensive perspective on obesity epidemiology, pathophysiology, and management. The chapters provide a better understanding of obesity-related diseases and offer an integrative framework for individualized dietary and exercise programs, behavior modification, surgery, and population interventions to reduce the growing epidemic of obesity.

Covering a wealth of information, the book:
  • shows the trend of obesity as an epidemiological concern
  • considers the genetic and environmental factors that contribute to the obesity epidemic
  • presents novel contributing factors and effects of obesity as a medical condition
  • discusses population-based treatments of obesity

CONTENTS:
Introduction
Chapter 1. Population Trends and Variation in Body Mass Index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort

Jason P. Block, S. V. Subramanian, Nicholas A. Christakis, and A. James O’Malley

Chapter 2. Community Energy Balance: A Framework for Contextualizing Cultural Influences on High Risk of Obesity in Ethnic Minority Populations

Shiriki Kumanyika, Wendell C. Taylor, Sonya A. Grier, Vikki Lassiter, Kristie J. Lancaster, Christiaan B. Morssink, and André M. N. Renzaho

Chapter 3. A Genome-Wide Association Study on Obesity and Obesity-Related Traits

Kai Wang, Wei-Dong Li, Clarence K. Zhang, Zuoheng Wang, Joseph T. Glessner, Struan F. A. Grant, Hongyu Zhao, Hakon Hakonarson, and R. Arlen Price

Chapter 4. Differences between Adiposity Indicators for Predicting All-Cause Mortality in a Representative Sample of United States Non-Elderly Adults

Henry S. Kahn, Kai McKeever Bullard, Lawrence E. Barker, and Giuseppina Imperatore

Chapter 5. A New Body Shape Index Predicts Mortality Hazard Independently of Body Mass Index

Nir Y. Krakauer and Jesse C. Krakauer

Chapter 6. Metabolically Healthy and Unhealthy Obesity Phenotypes in the General Population: The FIN-D2D Survey

Pia Pajunen, Anna Kotronen, Eeva Korpi-Hyövälti, Sirkka Keinänen-Kiukaanniemi, Heikki Oksa, Leo Niskanen, Timo Saaristo, Juha T. Saltevo, Jouko Sundvall, Mauno Vanhala, Matti Uusitupa, and Markku Peltonen

Chapter 7. Liver and Muscle in Morbid Obesity: The Interplay of Fatty Liver and Insulin Resistance

Mariana Verdelho Machado, Duarte M. S. Ferreira, Rui E. Castro, Ana Rita Silvestre, Teresinha Evangelista, João Coutinho, Fátima Carepa, Adília Costa, Cecília M. P. Rodrigues, and Helena Cortez-Pinto

Chapter 8. Sarcopenia Exacerbates Obesity-Associated Insulin Resistance and Dysglycemia: Findings from the National Health and Nutrition Examination Survey III

Preethi Srikanthan, Andrea L. Hevener, and Arun S. Karlamangla

Chapter 9. Prevalence of Obesity and Associated Cardiovascular Risk: The DARIOS Study

Francisco Javier Félix-Redondo, María Grau, José Miguel Baena-Díez, Irene R. Dégano, Antonio Cabrera de León, Maria Jesús Guembe, María Teresa Alzamora, Tomás Vega-Alonso, Nicolás R. Robles, Honorato Ortiz, Fernando Rigo, Eduardo Mayoral-Sanchez, Maria José Tormo, Antonio Segura-Fragoso, and Daniel Fernández-Bergés

Chapter 10. Obstructive Sleep Apnea Is a Predictor of Abnormal Glucose Metabolism in Chronically Sleep Deprived Obese Adults

Giovanni Cizza, Paolo Piaggi, Eliane A. Lucassen, Lilian de Jonge, Mary Walter, Megan S. Mattingly, Heather Kalish, Gyorgy Csako, and Kristina I. Rother, for the Sleep Extension Study Group

Chapter 11. Cluster Analysis of Obesity and Asthma Phenotypes

E. Rand Sutherland, Elena Goleva, Tonya S. King, Erik Lehman, Allen D. Stevens, Leisa P. Jackson, Amanda R. Stream, John V. Fahy, and Donald Y. M. Leung

Chapter 12. Diet, Physical Exercise and Cognitive Behavioral Training as a Combined Workplace Based Intervention to Reduce Body Weight and Increase Physical Capacity in Health Care Workers: A Randomized Controlled Trial

Jeanette R. Christensen, Anne Faber, Dorte Ekner, Kristian Overgaard, Andreas Holtermann, and Karen Søgaard

Chapter 13. Reduction in Adiposity, ?-Cell Function, Insulin Sensitivity, and Cardiovascular Risk Factors: A Prospective Study among Japanese with Obesity

Maki Goto, Akemi Morita, Atsushi Goto, Kijo Deura, Satoshi Sasaki, Naomi Aiba, Takuro Shimbo, Yasuo Terauchi, Motohiko Miyachi, Mitsuhiko Noda, and Shaw Watanabe, for the SCOP Study Group

Chapter 14. Bariatric Surgery: The Challenges with Candidate Selection, Individualizing Treatment and Clinical Outcomes

K. J. Neff, T. Olbers, and C. W. le Roux

Index


About the Authors / Editors:
Editor: Rexford S. Ahima, MD, PhD
Professor of Medicine, University of Pennsylvania Perelman School of Medicine, Division of Endocrinology, Diabetes and Metabolism, Philadelphia, Pennsylvania, USA

Dr. Rexford S. Ahima is a Professor of Medicine at the University of Pennsylvania. He received his BSc training at the University of London, MD at the University of Ghana, and PhD in neuroscience at Tulane University in New Orleans, Louisiana, internship and residency training in internal medicine at the Albert Einstein College of Medicine, New York, and clinical and research fellowships in Endocrinology, Diabetes and Metabolism at the Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston. Dr. Ahima’s research is focused on the actions of adipose hormones on energy homeostasis, and glucose and lipid metabolism. He is an elected member of the American Society for Clinical Investigation (ASCI), and the Association of American Physicians (AAP), and a fellow of the American College of Physicians (ACP), and The Obesity Society (TOS).




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