Pharmaceutical Science & Technology

Natural Products in Drug Discovery
Benefits, Challenges, and Opportunities

Editor: Meenakshi Thakur, PhD

Natural Products in Drug Discovery

In Production
Pub Date: Forthcoming August 2025
Hardback Price: $260 US | £210 UK
Hard ISBN: 9781998511280
Pages: Est. 565pp w/index
Binding Type: Hardback / ebook
Notes: 23 color and 127 b/w illustrations

Natural products are rich in bioactive compounds which can be explored for drug development. This new volume, Natural Products in Drug Discovery: Benefits, Challenges and Opportunities, combines the potential of traditional medicine with modern techniques for using products derived from natural sources such as plants, microbes, and marine sources as the basis for drug development.

This book presents information on the bioactive potential of natural products with properties that are antimicrobial, immunomodulatory, anti-cancerous, anti-inflammatory, hepatoprotective, antiviral, etc. and their usage in drug development. Recent techniques used for the isolation and identification of bioactive ingredients from natural sources have also been covered. The book reviews the latest developments in the field of genomics, transcriptomics, proteomics, and metabolomics for harnessing these natural products for commercial applications. The current status of bioprospection and commercialization of natural products-based drugs have also been reviewed.

Combining the potential of traditional medicine with modern techniques for the use of natural products for drug development, the book will serve as a useful reference for biochemists, phytochemists, pharmaceutical R&D professionals, students, and researchers working in the field of drug discovery from natural sources

CONTENTS:
Preface

1. Natural Products as Drug Candidates

Tooba Mahboob, Mogana Sundari Rajagopal, and Saad Tayyab

2. Traditional Knowledge for Drug Discovery
Tamanna, Kuldipika Sharma, Sanjeev Kumar, Neeraj Sankhyan, Yash Pal Sharma, Nitin Sharma, and Meenakshi Thakur

3. Herbal Healing: Plant-Based Natural Products
Anchal Sharma and Meenakshi Thakur

4. Natural Products with Antimicrobial Properties
María Melissa Gutiérrez Pacheco, Heriberto Torres Moreno, Ricardo Salomon Torres, Luis Alberto Ortega Ramírez, and Julio César López Romero

5. Natural Products with Immunomodulatory Properties
Rashim Kumari, Shriya Bhatt, Mahesh Gupta, and Rajat Rana

6. Natural Products with Anticancer Properties
Nidhee Chaudhary, Ogireddy Sri Apoorva, and Mansi Agrawal

7. Natural Products with Antiviral Properties
Maria Carolina Jasso Miranda

8. Approaches to Develop Drugs from Natural Products
Himani Sharma, Shivani Chauhan, Kavita Rana, and Preeti Sharma

9. Strategies for Isolation and Identification of Bioactive Molecules from Natural Sources
Hamid, Deepika Kathuria, Sunakshi Gautam, Shakshi Sharma, and Shweta Suri

10. Role of Omics in Natural Products-Based Drug Discovery
Bhagyabhumi Shah, Ruchi Yadav, Nilay Solanki, and Bhumika Patel

11. Natural Products from Endophytic Microorganisms
David C. Nwobodo and Peter M. Eze

12. Natural Products with Antidiabetic Properties
Kanchan Singh

13. Marine-Derived Natural Products with Anticancer Properties
Popat Mohite, Ramdas Pandhare, and Deshraj Chumbhale

14. Natural Products as Novel Opportunities for Cathepsin Inhibitors
Emerson Finco Marques

15. Phytoestrogens in Drug Discovery: A Focus on Mechanisms of Action and Safety Assessment
Bancha Yingngam

16. Honey Bee Products with Antimicrobial Properties
Jelena Ciric and Tatjana Baltic

17. Natural Products for the Prevention of Leaky Gut
Devi Basumatary, Pranamika Sarma, and Jagat C Borah

18. Role of Natural Products in the Pharmacotherapy of Osteoporosis
Raja Chakraverty, Somoshree Sengupta, and Tatini Debnath

19. Gel-Based Natural Therapeutics: Potential Alternatives to Traditional Drug Delivery Systems in Aquaculture
Suparna Deb, Bhavesh Choudhary, Jham Lal, Pradyut Biswas, and Soibam Khogen Singh

20. The Promising Role of Natural Products as Neuroprotective Agents
Ajaykumar Chittipolu, Nunavath Raja Shekhar, and Nimmala Shanthi

21. Natural Products from Microbes
Sharon Nagpal, Lenika Kashyap, Sanjula Sharma, Pooja, and Jomika Devi

22. Natural Product Databases: Discovering Natures Riches
Gaurav Kumar, Pankaj Barman, Rituraj Konwar, and Ravindra K. Rawal

23. Bioprospecting and Commercialization of Natural Products
Pankaj Barman, Gaurav Kumar, Kallol Roy, Ravindra K. Rawal, and Rituraj Konwar

Index


About the Authors / Editors:
Editor: Meenakshi Thakur, PhD
Assistant Professor (Biochemistry), College of Horticulture and Forestry (Dr. Yashwant Singh Parmar University of Horticulture and Forestry), Neri, Hamirpur, Himachal Pradesh, India

Meenakshi Thakur, PhD, is currently an Assistant Professor (Biochemistry) at the College of Horticulture and Forestry (Dr. Yashwant Singh Parmar University of Horticulture and Forestry), Neri, Hamirpur, Himachal Pradesh, India. Dr. Thakur research interests and contributions are on biotic and abiotic stress management in plants by employing various strategies such as use of elicitors/plant-based extracts or essential oils. She has published 29 research and review articles and nine book chapters. She was awarded an INSPIRE fellowship from the Department of Science & Technology (India) in 2011 for her doctorate research. She has won prestigious awards from the Association of Indian Universities, New Delhi, India (2013) and Honorable Jury Mention Certificate in Young Scientist Category by EET, CRS, India (2019). She received a travel grant from the Houghton Trust and British Poultry Science for participation at the 20th Congress of the World Veterinary Poultry Association at Edinburgh, Scotland (United Kingdom). She serves as an academic editor for PLOS One and is also a recognized reviewer for several journals.




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