Pharmaceutical Science & Technology

Natural Pharmaceuticals and Green Microbial Technology
Health Promotion and Disease Prevention

Editors: Debarshi Kar Mahapatra, PhD
Ravindra S. Shinde, PhD
Aishwarya A. Andhare
A. K. Haghi, PhD

Natural Pharmaceuticals and Green Microbial Technology

Published. Available now.
Pub Date: February 2021
Hardback Price: see ordering info
Hard ISBN: 9781771888813
E-Book ISBN: 9781003003229
Pages: 298 w/index
Binding Type: Hardback
Notes: 10 color and 88 b/w illustrations

This volume presents some of the latest research and applications in using natural substances and processes for pharmaceutical products. It presents an in-depth examination of the chemical and biological properties of selected natural products that are either currently used or have the potential for useful applications in the chemical and pharmaceutical industries. It covers emerging technologies and case studies and is a source of up-to-date information on natural products and microbial technology. It provides an applied overview of the field, from traditional medicinal targets to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract, and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery.

Topics include the safe use of use of petrochemical for various chemical and organic processes, the antibiotic and bio-herbicidal potential of extracts of Abutilon indicum and Prosopis juliflora, the health benefits of eugenol, stem cells and their connection with cancer, and more.

Scientists, industry professionals, and graduate students will gain a unique insight into green microbial technology and natural pharmaceuticals today along with their practical implementation for health promotion and disease prevention.

CONTENTS:
Preface

1. Green Solvents for Pharmaceuticals
Gokul S. Talele and Hitesh V. Shahare

2. Abutilon indicum and Prosopis juliflora as a Source of Antibiotic and Herbicidal Agents
Aishwarya A. Andhare and Ravindra S. Shinde

3. Pharmacological Perspectives of Eugenol in a Modern Context
Amena Ali and Abuzer Ali

4. Predictive in Silico Global Metabolism Analysis: Disease Mechanism
Francisco Torrens and Gloria Castellano

5. Intracellular Proteolysis and Neoplasia: Ubiquitin-Proteasome System, Cell Cycle, and Cancer
Francisco Torrens and Gloria Castellano

6. Vitamin D, Analogues, Drugs, and Their Relevance to Cancer Inhibition
Francisco Torrens and Gloria Castellano

7. Stem Cells and Their Connection with Cancer: Prostate Disease
Francisco Torrens and Gloria Castellano

8. MEK/ERK Pathway Overactivation in Liver Tumors: TGF B Death
Francisco Torrens and Gloria Castellano

9. Chalcone Scaffold Bearing Natural Anti-Gout Agents
Debarshi Kar Mahapatra, Vivek Asati, and Sanjay Kumar Bharti

10. Double–Pole Electrode in New Devices and Processes for Direct Electrochemical Oxidation of Blood Inside the Blood Vessel
V. A. Rudenok

11. Advanced Development in the Synthesis of Biologicaly Active Heterocyclic 1, 2, 3, 4 Tetrahydropyrimidine-2-Ones
Kalpana N. Handorea, Vasant V.Chabukswara, and S. B. Sharma

Index


About the Authors / Editors:
Editors: Debarshi Kar Mahapatra, PhD
Assistant Professor, Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India

Debarshi Kar Mahapatra, PhD, is currently Assistant Professor in the Department of Pharmaceutical Chemistry at Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India. He was formerly Assistant Professor in the Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, RTM Nagpur University, Nagpur, India. He has taught medicinal and computational chemistry at both the undergraduate and postgraduate levels and has mentored students in their various research projects. His area of interest includes computer-assisted rational designing and synthesis of low molecular weight ligands against druggable targets, drug delivery systems, and optimization of unconventional formulations. He has published research, book chapters, reviews, and case studies in various reputed journals and has presented his work at several international platforms, for which he has received several awards by a number of bodies. He has also authored the book titled Drug Design. Presently, he is serving as a reviewer and editorial board member for several journals of international repute. He is a member of a number of professional and scientific societies, such as the International Society for Infectious Diseases (ISID), the International Science Congress Association (ISCA), and ISEI.

Ravindra S. Shinde, PhD
Assistant Professor, Department of Chemistry and Industrial Chemistry, Dayanand Science College, Latur, Maharashtra, India

Ravindra S. Shinde, PhD, is presently serving as Assistant Professor, Department of Chemistry at Dayanand Science College, Latur, in Maharashtra, India. He has around 14 years of teaching experience at the BSc and MSc level. Having more than 23 research publications to his credit in journals of national and international repute, he is also the author of many undergraduate- and postgraduate-level books. He has published two books with Apple Academic Press: Green Chemistry and Sustainable Technology; Modern Green Chemistry and Heterocyclic Compounds, and one with Lulu Press, Inc. Morrisville, North Carolina: Practical Chemistry. He has also written chapters in books published by several other international publishers. Dr. Shinde has delivered lectures and chaired sessions at national conferences and is a reviewer for a number of international journals. In addition, he has completed minor research projects sponsored by different funding agencies. He is a university-approved recognized postgraduate teacher in chemistry. He has around one decade of administrative experience as National Service Scheme (NSS) programme officer, member of university exam committee, coordinator of a UGC-sponsored NET/SET coaching cell and One Teacher One Skill Committee of the college, and brand ambassador of online NPTEL examination run by Indian Institutes of Technology and Indian Institute of Science. He was awarded a number of prestigious awards during his career, such as Vidyabushan Puraskar by the Indian NET/SET Association (2010) and a National Teacher Award (2019).

Aishwarya A. Andhare
Research Scholar, Department of Microbiology, Dayanand Science College, Latur, India

Andhare A. Aishwarya is studying for her bachelor’s in microbiology at the Dayanand Science College, Latur, affiliated with Swami Ramanand Tirth Marathwada University, Nanded. She has a keen interest in research and has been chosen basic sciences as her career choice. She was actively doing research work from first year. Ms. Aishwarya has published eight papers in international journals (UGC, NAAS approved). She had actively participated in several research competitions and has won more than forty prizes in various competitions, including sports, drawing, debates, elocutions and many more. She has published an international book, Astonishing Reviews of Nature towards Nature (LAMBERT Academic Publishing of Germany), and she has also written many chapters in edited books. She had been selected for many summer research fellowship programs organized by the Jawaharlal Nehru Center for Advanced Scientific Research, Jakkur P.O., Bengalore and under the CSIR-NCL SDP program held at the CSIR-National Chemical Laboratory, Pune, India. She has presented papers (both oral and poster) at more than 12 international conferences. The Dayanand Education Society has awarded her 50,000 Rs for research funding. Her research work is on “Seeking Hidden Potentials of Nature and Discovering Something New from Natural Ingredients.” Along with her academic responsibilities, she is interested in social works and has been named “Best Volunteer of NSS” for two continuous and now trying to be a NCC cadet.

A. K. Haghi, PhD
Professor Emeritus of Engineering Sciences, Former Editor-in-Chief, International Journal of Chemoinformatics and Chemical Engineering and Polymers Research Journal; Member, Canadian Research and Development Center of Sciences and Culture

A. K. Haghi, PhD, is the author and editor of 165 books, as well as 1000 published papers in various journals and conference proceedings. Dr. Haghi has received several grants, consulted for a number of major corporations, and is a frequent speaker to national and international audiences. Since 1983, he served as professor at several universities. He is former Editor-in-Chief of the International Journal of Chemoinformatics and Chemical Engineering and Polymers Research Journal and is on the editorial boards of many international journals. He is also a member of the Canadian Research and Development Center of Sciences and Cultures (CRDCSC), Montreal, Quebec, Canada.




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