Pharmaceutical Science & Technology

DNA- and m-RNA-Based Vaccines
An Immunotherapeutic Approach to Cancer

Sonali Sundram, MPharm
Rishabha Malviya, PhD

DNA- and m-RNA-Based Vaccines

In Production
Pub Date: Forthcoming February 2025
Hardback Price: $200 US | £150 UK
Hard ISBN: 9781774919606
Pages: Est. 316pp w/index
Binding Type: Hardback / ebook
Notes: 19 color and 2 b/w illustrations


Reviews
“Pioneers in the field of cancer research and immunotherapy, Sonali Sundram and Dr. Rishabha Malviya have put together an extensive book that explores the cutting-edge application of messenger RNA (m-RNA) and DNA vaccines to target and eradicate cancer. . . . A collection of contemporary scientific studies on the relevant topics that can be very useful to the scientists working in these areas for future strategies and be an invaluable source of motivation for everyone involved in the battle against cancer.”
—From the Foreword by Roop Krishen Khar, Director, B. S. Anangpuria Educational Institutes, Faridabad; Director, Formulators Koncept Pvt. Ltd. and Unicure India Ltd.; Former Dean, Jamia Hamdard University, New Delhi, India


One of the most novel and promising strategies in medical research and the fight against cancer is the combination of DNA and messenger RNA (m-RNA) vaccines. This new book, DNA- and m-RNA-Based Vaccines: An Immunotherapeutic Approach to Cancer, explores the therapeutic uses, biological processes and the difficulties related to this novel strategy for cancer immunotherapy in great detail.

This book explores the power of genetic material in the battle against cancer and investigates the many aspects of this groundbreaking strategy. Offering a unique perspective on various different facets of DNA- and mRNA-based cancer vaccines, the authors present a thorough overview of the constantly changing field of cancer immunotherapy, from explaining the unique aspects of tumor angiogenesis and the role that non-coding RNAs play in treatment resistance, to investigating the most recent developments in gene therapy and splicing control. The volume also looks at this fascinating field’s future potential, giving cancer patients hope for less intrusive and more effective therapies.

Key features:

  • Presents a thorough investigation of cancer vaccines based on DNA and m-RNA
  • Discusses gene therapy, tumor angiogenesis, and the function of non-coding RNA in treatment resistance
Revealing the latest and most comprehensive information on DNA and m-RNA vaccines, and providing a fresh and exciting approach that has the potential to revolutionize how we think about cancer treatment, this book will be an invaluable resource for researchers, physicians, students, and everyone interested in the most recent advancements in cancer therapy and vaccination technology.


CONTENTS:
Preface

1. Various Prospects of Tumor Angiogenesis

2. Cancer Treatment Through Gene Therapy: Methods, Challenges, and Current Progress

3. Current Status and Prospects for Cancer Gene Therapy

4. Therapeutic Interventions and Non-Coding RNA-Mediated Mechanisms of Cancer Resistance

5. The Role of Splicing as a Therapeutic Target of Cancer

6. Cancer DNA Vaccines: Inducing Efficient Immunity

7. Innovative DNA Vaccines That Utilize Pinpoint Precision Technology to Effectively Stimulate the Immune System Against Cancer

8. Utilizing DNA Vaccines and Electroporation to Fight Cancer

9. Promoting DNA-Based Cancer Vaccine Research

10. Cancer Immunotherapy Using a DNA Vaccination

11. Cancer Vaccine Based on Plasmid DNA and Messenger RNA


Index



About the Authors / Editors:
Sonali Sundram, MPharm
Assistant Professor, School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh India

Sonali Sundram, MPharm, is Assistant Professor in the School of Medical & Allied Sciences at Galgotias University, Greater Noida, Uttar Pradesh, India. Previously, she worked as a research scientist on a project of the Indian Council of Medical Research at King George’s Medical University, Lucknow, India. After that, she joined the Babu Banarasi Das Northern India Institute of Technology (BBDNIIT), Lucknow. Her PhD (Pharmacy) work is in neurodegeneration and nanoformulation. Her areas of interest include neurodegeneration, clinical research, and artificial intelligence. She has edited four books (Wiley, CRC Press/Taylor and Francis, River Publisher) and has organized more than 15 national and international seminars, conferences, and workshops. She has more than eight patents, both national and international, to her credit. She completed both her BPharm and MPharm (Pharmacology) at Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India.

Rishabha Malviya, PhD
Associate Professor, Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India

Rishabha Malviya, PhD, has 11 years of research experience and is presently working as Associate Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India. His areas of interest include formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 150 research and review papers for national and international journals of repute. He has over 50 patents to his name and many publications in reputed national and international journals (with a total of 91 cumulative impact factor). He has also received an Outstanding Reviewer Award from Elsevier. He has edited books (Wiley, Springer Nature, CRC Press/Taylor and Francis, Apple Academic Press, River Publisher, Lambert, etc.) and authored 15 book chapters. His name has been included in the Stanford University’s World’s Top 2% Scientists, 2020 by Elsevier BV and Stanford University. He is a reviewer, editor, and editorial board member of more than 50 national and international journals. He was an invited author for the magazine Atlas of Science as well as a pharma magazine dealing with the B2B industry, Ingredients South Asia .He completed his BPharm at Uttar Pradesh Technical University and MPharm (Pharmaceutics) at Gautam Buddha Technical University, Lucknow, Uttar Pradesh, India. His PhD (Pharmacy) work was in novel formulation development techniques.




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