Chemistry

Clinical Biochemistry and Drug Development
From Fundamentals to Output

Editor: Shashank Kumar, PhD

Clinical Biochemistry and Drug Development

Published. Available now.
Pub Date: November 2020
Hardback Price: see ordering info
Hard ISBN: 9781771888691
E-Book ISBN: 9780367821470
Pages: 264pp w/index
Binding Type: Hardback
Notes: 6 color and 22 b/w illustrations

This book, Clinical Biochemistry and Drug Development: From Fundamentals to Output, focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development. The book introduces cell animal and bacterial culture techniques and their potential uses as well as cell culture techniques. The biochemistry aspect of the book covers the principles of clinical biochemistry and biochemical analysis, biochemical aids to clinical diagnosis, measurement, and quality control. The book also presents important concepts in cell membrane receptor signal transduction pathways as drug targets. The drug development focus of the book discusses the fundamentals of human disease and drug discovery. Various in silico, in vitro, and in vivo approaches for drug discovery are examined, along with a discussion on drug delivery carriers and clinical trials. Overall, the volume provides an overview of the journey from clinical fundamentals to clinical output.

The book aims to provide an understanding for the students of health science and life sciences. This book involves the fundamentals of clinical biochemistry and use of cell culture techniques. Furthermore the book will discuss the fundamentals of drug discovery and development. Over the entire book will cover the journey from clinical fundamentals to clinical output.

CONTENTS:
Preface

1. An Introduction to Cell Culture
Amit Kumar Sharma, Atul Kumar Singh, and Shashank Kumar

2. Animal Cell Culture
Amit Kumar Sharma, Atul Kumar Singh, Mohammad Waseem, and Shashank Kumar

3. Bacterial Cell Culture
Amit Kumar Sharma, Santosh Kumar Maurya, and Shashank Kumar

4. Potential Use of Cell Cultures
Amit Kumar Sharma, Atul Kumar Singh, Hadiya Husain, and Shashank Kumar

5. Principles of Clinical Biochemistry and Biochemical Analysis
Shashank Kumar

6. Biochemical Aids to Clinical Diagnosis
Prem Prakash Kushwaha, P. Seshu Vardhan, K. Vishnupriya, Sharmistha Singh, and Shashank Kumar

7. Clinical Measurements and Quality Control
Prem Prakash Kushwaha, P. Seshu Vardhan, M. S. Sandeep Vedanarayana, and Shashank Kumar

8. Cell Membrane Receptor
Prem Prakash Kushwaha, Swastika Dash, Atul Kumar Singh, and Shashank Kumar

9. Mechanisms of Signal Transduction
Prem Prakash Kushwaha, Rebati Malik, P. Seshu Vardhan, Shiv Govind Rawat, Sharmistha Singh, and Shashank Kumar

10. Human Disease Drug Therapy and Drug Discovery
Prem Prakash Kushwaha, Rebati Malik, P. Seshu Vardhan, Shiv Govind Rawat, Atul Kumar Singh, and Shashank Kumar

11. Drug Development: In Silico, In Vivo and System Biology Approach
Prem Prakash Kushwaha, Rebati Malik, Shiv Govind Rawat, Atul Kumar Singh, and Shashank Kumar

12. Drug Development: Drug Delivery Carriers and Clinical Trial
Prem Prakash Kushwaha, Swagata Das, Atul Kumar Singh, and Shashank Kumar

13. Role of Micro RNA in Prostate Cancer Therapy
Mohammad Waseem Hadiya Husain and Imran Ahmad

14. Pathogenesis, Molecular Mechanisms of Progression, and Therapeutic Targets of Liver Fibrosis: An Update
Hadiya Husain and Riaz Ahmad

15. Prostate Cancer: Molecular Aspects, Biomarkers, and Chemo-Preventive Agents
Risha Ganguly, Abhay K. Pandey, Prem Prakash Kushwaha, and Shashank Kumar

16. Overview of Tuberculosis Biomarkers: An Update
Abhilasha Tripathi, Surya Kant, Prem Prakash Kushwaha, and Shashank Kumar

Index


About the Authors / Editors:
Editor: Shashank Kumar, PhD
Assistant Professor, Department of Biochemistry and Microbial Sciences, Central University of Punjab, India

Shashank Kumar, PhD, is an Assistant Professor in the Department of Biochemistry and Microbial Sciences at the Central University of Punjab, India. He previously worked as Post-Doctoral Fellow at the Department of Biochemistry at King George’s Medical University, India. Dr. Kumar has edited several books, including Concepts in Cell Signaling; Secondary Metabolites and Functional Food Components; Carbohydrate Metabolism Theory and Practical Approach; Phytochemistry: An in silico and in vitro Update; etc. Dr. Kumar has more than 30 published scientific papers/reviews/editorial articles in various national and international peer-reviewed journals of repute. He has expertise in the areas of free radical biology, cancer biology, cell culture techniques, characterization of plant products, xenobiotic metabolism, and microbiology. He has presented his research findings at more than 25 national/international conferences and has attended many workshops at the most of major universities and medical colleges throughout India. Dr. Kumar is an academic/editorial board member and reviewer of about 25 international journals. Dr. Kumar is a lifetime member of the Italo-Latin American Society of Ethnomedicine and Indian Sciences Congress Association and is member of Publication Integrity & Ethics, London. Dr. Kumar received his BSc, MSc, and PhD degrees in biochemistry from the Department of Biochemistry, University of Allahabad, India




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