|
Pharmaceutical Science & Technology
The proposed book will comprehensively discuss about the enzymes such as E1, E2, E3 ligases, deubiquitinating enzymes including proteins which control neurodegenerative disease-inducing proteins, but also their potentials as a therapeutic agent for neurodegenerative diseases. Deubiquitinating enzymes regulates toxic proteins inducing neurodegenerative diseases through proteasome signaling, mitophagy, autophagy etc, for the mitigation of brain disorders. In addition to that, we are going to address biological role of the transglutaminases in the neuroinflammation, with particular interest in the molecular mechanisms, which could involve these enzymes in the pathophysiological processes of human neurodegenerative diseases. Further, the proposed book will also be helpful to explore promising therapeutic targets from highly dynamic ubiquitination modification processes. Only a few numbers of molecules will reach to the market after an extensive effort of researcher in clinical trials. Most of the molecules in the market available for neurodegenerative disorders are not targeted specific and showing severe-side effects and toxicity. Acetylcholinesterase inhibitors and glutamate blockers are available to moderate-severe ND. However, poor blood brain barrier (BBB) permeability and neuronal toxicity are the limitations of existing drugs. So, considering the above-mentioned scientific facts, there is need of development of target specific drug delivery for neurodegenerative disorders. So, in the proposed book, we are going to discuss about the novel targets involved in neurodegeneration and summaries all advance research and formulation strategies to target the neurodegenerative disorders for the safe and effective management of neurodegenerative disorders. CONTENTS: About the Authors / Editors: Editors: Dr. Prashant Tiwari, PhD Associate Professor, Department of Pharmacology, College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, India Dr. Prashant Tiwari, Ph.D., is currently working as an Associate Professor in the Department of Pharmacology at the College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, India. He has gained experience of over a decade in the field of teaching and research related to pharmacology. He received his Ph.D. from Siksha O Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India. He was a regular fellow of the ICMR, New Delhi. India. He has rich teaching and research experience of more than 13 years of experience in working on screening of several drugs and method validation for the effective delivery of drugs towards brain cell. He has gained experience revalidation of the drug induced dyskinesia and evaluation of the effect of benzimidazole derivative on dopaminergic pathway. He also has riches experience on synthesis of benzimidazole derivative and its prolactin inhibitory effect against neuroleptic drug induced hyperprolactinemia. In addition, to that he was actively involved for the evaluation of Neuroprotective effect of Nanoemulsions containing Lepidium sativum oil against Parkinson's disease. Further, he has direct association for the evaluation of Neuroprotective effect of Muntingia Calabura leaf extract against Alzheimer's Disease for which Dr. Tiwari was awarded Dr. P. D. Patil National Award for Best Thesis in Pharmaceutical Sciences-2022 organized by Dr. P. D. Patil National Institute of Pharmaceutical Sciences and Research, Pune. The team is awarded Third position in the subject category Pharmacology. He has published more than 50 quality research papers along with reviews in journals of high repute, h-index 13, i10 index 18 and 730 citations. He has authored 5 books, edited 4 books, co-authored 06 book chapters and filed 7 patents with 2 patents granted. Dr. Tiwari had organised nation e-seminar titled 'Targeted Drug Delivery System Against Neurodegenerative Diseases' Sponsored by Department of Biotechnology (DBT), New Delhi, Ministry of Science and Technology, Government of India. He has also engaged several accolades like the ICMR SRF, CCSTDST travel grant award for research paper publication. He holds the membership of several nationally and internationally recognized bodies of repute like the LASAI, INS, APTI, IPES, SPER, ERDA etc. He has several awards in his recognition such as Dr. P. D. Patil National Award for Best Thesis in Pharmaceutical Sciences-2022, Young Scientist Award, Young Talent Award, and Best Teacher Award. He is a peer reviewer of various international Journals and publishers. He has guided 06 M Pharm students for their dissertations/research projects and 4 Ph.D. students continuing their research work under his guidance out of which one research fellow has submitted PhD thesis. His research areas include Neurodegenerative disorders, drug interaction, PK/PD, and metabolic disorders. Dr. K. Sunil Kumar Professor, College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, Karnataka, India Dr. K. Sunil Kumar is currently working as Professor in the College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, Karnataka, India. He has 16 years of experience in teaching. His area of interest is in Neuropharmacology. He has completed his Ph.D. in Pharmaceutical Sciences from JNTU Hyderabad, Telangana. He has 52 research and review publications in his credit. He has 4 books and 3 patents in his credit. He is a professional member of APTI. His area of Interest is Neuropharmacology and Drug interactions. Dr. Kunjbihari Sulakhiya Assistant Professor, Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak (M.P.), India Dr. Kunjbihari Sulakhiya is working as an Assistant Professor at the Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak (M.P.). He has obtained his M.S. (Pharm) and Ph. D. in Pharmacology and Toxicology from the National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India. He has published 17 research papers, 7 review articles and 10 book chapters in reputed peer-reviewed international and national journals and books. He has received 11 awards/fellowships including 6 travel awards to present his research papers at international conferences in the USA, Canada, Japan, France, and Macau. He is a member of various professional societies including the Indian Academy of Neurosciences (IAN), the International Society for Neurochemistry (ISN), Asia Pacific Society for Neurochemistry (APSN), APTI etc. He is serving as an editorial member and reviewer for various reputed journals. His area of research is pre-clinical research in the field of neuropharmacology. |
Follow us for the latest from Apple Academic Press:
AAP WELCOMES PROF. MOHAMMED KUDDUS, PhD, AS AAP’S NEW ACQUISITIONS EDITOR for books on biotechnology, enzymology, microbiology, bioinformatics, bioremediation, biomedical technology, value-added products etc. Dr. Kuddus is Head of the Department of Biochemistry at the College of Medicine, University of Hail, Kingdom of Saudi Arabia. He is listed in Elsevier/Stanford University World’s Top 2% Scientists. He seeks book proposals from potential editors to consider for publication with Apple Academic Press. Contact: kuddus@appleacademicpress.com for more information.
AAP welcomes Dr. Maulin P. Shah as AAP’s new acquisitions editor for books on Applied Microbiology, Environmental Biotechnology and Waste Management. Dr. Shah, a Scientist in the Industrial Wastewater Research Lab at Enviro Technology Ltd., India. seeks book proposals to consider for these topics and related areas: applied microbiology, environmental biotechnology and waste management, including environmental pollution, wastewater treatment, bioenergy, biofuel, circular economy, leachate treatment activated sludge process, environmental microbiology, agricultural microbiology, advance oxidation process, bio-electrochemical systems, bacterial genomics for wastewater treatment, and heavy metal remediation. maulinshah1979@gmail.com for more information. AAP is pleased to announce Shrikaant Kulkarni, PhD, as our new Senior Commissioning Editor for books in the areas of Polymer Sciences, Chemical Sciences, Nuclear Sciences, and Material Sciences. Dr. Kulkarni is Adjunct Professor, Faculty of Business, Victorian Institute of Technology, Melbourne, Australia; and Adjunct Professor, Centre of Research Outcome and Impact, Chitkara University, Punjab, India. You can reach him at Email: srkulkarni21@gmail.com for more information. New Book Series: AAP Series on Waste Biomass Valorization will explore the transformation of biomass resources into valuable products, addressing the growing need for sustainable alternatives to fossil fuels and non-renewable resources. For more information and to propose a book, please visit: Click here Congratulations to Hafiz Ansar Rasul Suleria, PhD, for receiving the Dean’s Award for Excellence in Research from the University of Melbourne, Australia, in recognition for his exceptional performance and strong commitment to advanced research in food science. Dr. Suleria is editor of AAP’s book series Innovations in Plant Science for Better Health: From Soil to Fork. For more information, visit: Click here Congratulations to Dr. Christian Mancas. His book Conceptual Data Modeling and Database Design: A Fully Algorithmic Approach was one of the 6 Best Data Modeling ebooks for Beginners by BookAuthority, a leading site for book recommendations. For more information, visit: Click here COMMENTS FROM AAP EDITORS AND AUTHORS AAP book title: Advances in Audiology and Hearing Science (2-volume set) “I have collaborated with AAP during the process of bringing my two-volume editing work to a final publishing phase. AAP support has been truly important throughout the initial and final stages of the book. While the majority of the publishing work is done at the early stages, the final touches that include the last-minute corrections of the authors are extremely crucial to the quality the book tries to convey. The assistance of AAP during the last stages of corrections and communication with the authors was a very positive contributor to my state of mind during those stressful moments. I recommend the publishing experience with AAP to other editors of scientific material.” —Stavros Hatzopoulos, PhD, Hearing Science Laboratory, University Hospital of Ferrara, Ferrara, Italy AAP book title: Nanotechnologies: The Physics of Nanomaterials (2-volume set) “I was very pleased with the interaction and support of the team at Apple Academic Press. They provided me with regular and useful information and updates throughout the publishing procedure. I am also very happy with the final product, which is of good quality. The books are now available and are professionally distributed through the various channels. I would like again to thank the team at AAP for all their hard work and support.” —David Schmool, PhD, Director, Groupe d’Etude de la Matière Condensée GEMaC, National Centre for Scientific Research, Université de Versailles/Saint-Quentin, Université Paris-Saclay,Versailles, France AAP book title: Physiology of Molluscs (2-volume set) “I have enjoyed the full benefit of support, encouragement, and kindness from the members of AAP I have had the pleasure of being associated with. In the same vein, I hope AAP was satisfied with the book series I have edited in advancing the knowledge. It has been a great journey and was a great pleasure and satisfaction. Advancing scholarship through publications is one of the best routes publishers can take, and I would hold AAP as one of the best ones.” —Saber Saleuddin, PhD, University Professor Emeritus, Department of Biology, York University in Toronto, Ontario, Canada AAP book title: Green Chemistry and Sustainable Technology: Biological, Pharmaceutical, and Macromolecular Systems “It had been my pleasure to work with the production team of Apple Academic Press for almost a decade. The best presentation of our work was due to their hard work and with careful scrutiny. I am sure that every one of them takes extra pains to publish the book nicely, maintaining the quality and timeliness. It was a rewarding experience to work with AAP. I would like to publish more with AAP on my upcoming projects in future also.” —Prof. Suresh C. Ameta, Professor of Eminence (Distinguished Professor), Faculty of Science, PAHER University, UDAIPUR, India AAP book title: New Frontiers in Nanochemistry, 3-volume set, plus many others "Publishing a book, either as author or editor, is a journey from the initial vibration to the piece of knowledge towards the present future of humanity at large. Such a journey is about climbing and tunneling, about diving and driving through, about inspiration and tuning, about hard working in every instance; and it is also about time. Very few Global Publishers have the wisdom and patience and kindness and openness to authors, contributors, and readers while being truly crafting oriented as Apple Academic; yet all is about people and their education, vision and assumed mission; the Apple Academic Team heartily succeed that in achieving the world class scholarly acclaim by the quality involvement in all chain of plus value added with each publishing event. Hearty Compliments! Excelsior Apple Academic!" —Mihai V. Putz, PhD, Dr.-Habil., MBA, Professor, Faculty of Chemistry, Biology, Geography, Laboratory of Computational and Structural Physical Chemistry for Nanosciences and QSAR, West University of Timi?oara; PI-1, Laboratory of Renewable Energies - Photovoltaics, National Research and Development Institute for Electrochemistry and Condensed Matter (INCEM), Timi?oara, Romania AAP book title: The Chemical Century: Molecular Manipulation and Its Impact on the 20th Century “All my experiences with AAP have been very positive. I entrusted AAP with the publication of The Chemical Century: Molecular Manipulation and Its Impact on the 20th Century and found the quality of the book that they produced to be excellent. My two contacts at the company were very responsive and efficient throughout the publication process.” —Richard J. Sundberg, PhD, Professor of Chemistry, University of Virginia, Charlottesville, Virginia, USA AAP book titles: Medical Tourism and Wellness: Hospitality Bridging Healthcare (H2H)© and Medical Travel Brand Management: Success Strategies for Hospitality Bridging Healthcare (H2H) “I have enjoyed my scholarly creative work with Apple Academic Press. They have been timely, creative, and very helpful for my two books with them. I encourage you to consider publishing your work with AAP.” —Frederick DeMicco, PhD, RDN, Executive Director and Professor School of Hotel and Restaurant Management, Northern Arizona University, Flagstaff, Arizona AAP book title: The Chemical Evolution of Phosphorus: An Interdisciplinary Approach to Astrobiology “I’m very pleased with the books you have edited. It shows a very good and careful work by everyone involved along the whole production process, and so the final result is a beautiful piece: it has come out as a very nice and appealing book, easy to handle and read, .... and hopefully of interest for people from diverse related fields!” —Enrique Macia-Barber, PhD, Professor of Condensed Matter Physics, Universidad Complutense de Madrid, Spain |
