Plant Science & Botany

Antidiabetic Plants for Drug Discovery
Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity

Editors: Deepu Pandita
Anu Pandita
Chander Bhanu

Antidiabetic Plants for Drug Discovery

Published. Available now.
Pub Date: December 2022
Hardback Price: see ordering info
Hard ISBN: 9781774910061
E-Book ISBN: 9781003282938
Pages: 342pp w/index
Binding Type: Hardback / ebook
Notes: 9 color and 20 b/w illustrations

This volume takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives.

Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as flavonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs

Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology. The specific plants discussed include Azadirachta indica (commonly known as neem, nimtree or Indian lilac), Gymnema sylvestre (commonly called gymnema, Australian cowplant, and Periploca of the woods), Syzygium cumini (commonly known as Malabar plum, Java plum, black plum, jamun or jambolana), Ceylon cinnamon (or true cinnamon, as opposed to cassia cinnamon), insulin plant (or Costus pictus), Trigonella foenum-graecum (better known as fenugreek), Mulberry, Nigella sativa L. (black caraway, also known as black cumin, nigella, kalojeera, kalonji or kalanji), Aegle marmelos (L.) (commonly known as bael (or bili or bhel), also Bengal quince, golden apple, Japanese bitter orange, stone apple or wood apple), Ficus benghalensis (the banyan, banyan fig and Indian banyan), and of course, garlic (Allium sativum).

Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity will serve as a valuable source of information for students, drug researchers, medical practitioners, diabetic patients, and many others in the effort to gain understand of how these plant drug molecules can help fight diabetes.

CONTENTS:

Preface

1. Azadirachta indica: Its Biological, Pharmacological, Antidiabetic Potential, and Omics Applications
Vincent Ezin and Ifagbemi Bienvenue Chabi

2. Gymnema sylvestre (Asclepiadaceae): Multi-Potent Medicinal Plant with Potential for Antidiabetes and Obesity
Ramachandra Reddy Pamuru, Ambedkar Yarrapalle, and D. Vijaya Lakshmi

3. Perspectives of Syzygium cumini (L.) Skeels, as a Promising Rational Herbal Medicine for Diabetes
Lepakshi Md. Bhakshu, K. Venkata Ratnam, Deepu Pandita, Anu Pandita, Pulala Raghuveer Yadav, and R. R. Venkata Raju

4. Cinnamomum zeylanicum: Nature’s Wonder Plant with Antidiabetic Prominence
Sasireka Rajendran, Anu Pandita, Vinoth Rathinam, Sugumari Vallinayagam, Deepu Pandita, and Madheswaran Muthusamy

5. Antidiabetic Potential of the Insulin Plant (Costus pictus)
Kavita Rani, Swati Priya, Narender Singh, and Ruchi Bansal

6. Health Benefits of Trigonella foenum-graecum with Regard to Metabolomics of Antidiabetic Efficiency
Neha Sharma, Rajesh Singh Tomar, and Shuchi Kaushik

7. Mulberry: From Root to Fruit with Antidiabetic Properties
Masarat Bashir and Ashraf Dar

8. The Antidiabetic Effect of Nigella sativa L. with Respect to Its Phytochemicals and the Mechanism of Action
Iffat Zareen Ahmad

9. Aegle marmelos (L.) as a Functional Food for Managing Diabetes Mellitus
Khyatie Anjaria, Himanshu Dawda, Karishma Rajbhar, and Usha Mukundan

10. Garlic (Allium sativum): A Potential Antidiabetic Agent
Prabhash Kumar Pandey, Jayant Dewangan, Shambhoo Sharan Tripathi, Ranjan Singh, Farrukh Jamal, and Srikanta Kumar Rath

11. Antidiabetic Potential of Ficus benghalensis
Diksha Kapoor and Tabassum Khan

Index


About the Authors / Editors:
Editors: Deepu Pandita
Senior Lecturer, Government Department of School Education, Jammu, Union Territory of Jammu and Kashmir, India

Deepu Pandita is working as a Senior Lecturer in the Government Department of School Education, Jammu, Union Territory of Jammu and Kashmir, India. Deepu Pandita has more than 19 years of teaching experience and has a master’s in Botany from the University of Kashmir, Jammu and Kashmir, India, and a master’s in Philosophy in Biotechnology from the University of Jammu, Jammu and Kashmir, India. Deepu Pandita has a number of international and national courses to her credit. Deepu Pandita has qualified for fellowships, such as JRF-NET and SRF from the Council of Scientific and Industrial Research (CSIR), New Delhi India; Biotechnology Fellowship, Government Department of Science and Technology, Jammu & Kashmir, India; and IASC-INSA-NASI Summer Research Teacher Fellowship, India. Deepu Pandita has presented her research work at both national and international conferences and was awarded Best Oral Presentation Award at an International Conference on Biotechnology for Better Tomorrow, a Women Researcher Award, and a Research Excellence Award from two professional associations in India. Deepu Pandita is a life member of various science societies. Deepu Pandita acts as a reviewer (18 journals), associate editor, and editor of a number of international journals. Deepu Pandita has published a number of editorials, book chapters (Springer, CRC, and Elsevier), reviews, and research articles in various journals of national and international repute.

Anu Pandita
Dietician, Vatsalya Clinic, New Delhi, India

Anu Pandita is working as a Dietician at Vatsalya Clinic, E-5/11, Krishna Nagar, New Delhi, India. Previously she worked as a lecturer at Bee Enn College of Nursing, Talab Tillo, Jammu, India, and Dietician at Ahinsa Dham Bhagwan Mahavir Charitable Health Centre, New Delhi, India. Anu Pandita has done her MSc internship and a course in the Dietetics Department of PGI, Chandigarh, India. Anu Pandita conducted a case study at the Pediatric Gastroenterology Ward at Nehru Hospital, PGI, Chandigarh, India, on a patient suffering from chronic liver disease. She has done a Certificate in Food & Nutrition as well. She has a number of trainings, refresher courses, and workshops to her credit. Anu Pandita is a life-time member of the Indian Dietetic Association and Indian Science Congress Association, Kolkata, India. Anu Pandita has published for book chapters in Springer journals and a number of reviews and research articles in various journals of national and international repute. Anu Pandita has presented her research work at both the national and international conferences.

Chander Bhanu
Senior Consultant Physician, Vatsalya Clinic; Dr. Kailash Chander Jain Memorial Clinic; Ahinsa Dham Bhagwan Mahavir Medical Center, New Delhi, India

Chander Bhanu is a Senior Consultant Physician at the Vatsalya Clinic; at the Dr. Kailash Chander Jain Memorial Clinic; and at the Ahinsa Dham Bhagwan Mahavir Medical Center, all in New Delhi, India. Previously he was a neuro associate at the Institute of Brain and Spine; resident medical officer in at theVidya Sagar Institute of Mental Health and Neurosciences) Hospital, New Delhi; a chief medical officer at Primus Hospital, where handled international cases from various embassies; and a medical officer in the Neurology and Neurosurgery Departments at Fortis Hospital. He has expertise and experience in various clinical procedures such as pleural tapping, ascitic tapping, lumbar puncture, suturing, and other procedures both in pediatrics and adult groups and deals with stroke and accident cases as well. Dr. Bhanu earned his Bachelor of Medicine and Bachelor of Surgery) from Govt. Medical College, Calicut, Kerala, and a Post Graduate Diploma in Diabetes and Clinical Endocrinology from the Royal College of Physicians, United Kingdom. Dr. Chander Bhanu has certification in diabetes mellitus accredited by Royal Liverpool Academy, United Kingdom




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