Plant Science & Botany

Innovations in Plant Science for Better Health: From Soil to Fork

Anti-Coronavirus Marine Bioactive Compounds
Editor: Jen-Tsung Chen, PhD

Anti-Coronavirus Marine Bioactive Compounds

In Production
Pub Date: Forthcoming May 2025
Hardback Price: $240 US | £180 UK
Hard ISBN: 9781779640109
Pages: Est. 478pp w/index
Binding Type: Hardback / ebook
Series: Innovations in Plant Science for Better Health: From Soil to Fork
Notes: 18 color and 24 b/w illustrations

This unique volume, Anti-Coronavirus Marine Bioactive Compounds, summarizes emerging approaches based on in silico, in vitro, in vivo, and clinical studies to uncover the potential and the underlying mechanisms of diverse marine bioactive compounds to inhibit SARS-CoV-2 and its variants and, hence, pave the way for drug discovery devoted to the management of COVID-19.

Investigating a range of natural compounds for their anti-SARS-CoV-2 activity, this volume offers in-depth insights into molecular mechanisms that can inhibit viral/host protein targets of SARS-CoV-2. It highlights the action of marine bioactive compounds based on advanced bioinformatics tools such as molecular docking, computer simulation, and systems pharmacology, as well as multiple omics and high-throughput technologies. Chapters discuss the modes of action by selected marine polysaccharides, terpenoids, astaxanthin, and an indole-alkaloid (holyrine A) for combating SARS-CoV-2, and propose their potential role in COVID-19 management. Finally, a chapter discusses the role of marine bioactive compounds that include some traditional remedies from Southeast Asia for combating SARS-CoV-2 infection.

Key features:

  • Focuses on the therapeutic potential of marine bioactive compounds against SARS-CoV-2
  • Discusses the modes of action of marine bioactive compounds for anti-SARS-CoV-2 management
  • Summarizes the emerging findings on the pharmacology of marine bioactive compounds
Providing valuable knowledge based on state-of-the-art literature that highlights the anti-SARS-CoV-2 activity of marine bioactive compounds, this work will be an important resource for researchers, professors, and experts in diverse sub-fields of life sciences, such as virology, pharmaceutical science and drug discovery, medical research, biochemistry, bioinformatics, biomedical science, computational biology, epidemiology, and other areas. The book presents approaches that are potentially useful for the management of global public health and can support the goal of establishing “Good Health and Well-Being,” which is one of the “Sustainable Development Goals (SDGs) 2030" of the United Nations.

CONTENTS:
Preface

1. Marine Bioactive Compounds as Efficient Antiviral Agents Against SARS-CoV-2: An Overview

Debapriya Dutta, Ramansu Goswami, Sangita Lahiri, Sangjukta Roy, Ankita Chakraborty, and Suprabhat Mukherjee

2. Marine Bioactive Compounds for Combating SARS-CoV-2 Variants in the Post-Epidemic Era: A Molecular Insight and Prospects
Arockia Doss Cibile, Puzhakkal Abhirami, Natarajan Pushpa, Chenniappan Anchana Devi, Kalaiyarasan Vijayarani, Aasivtham Alwin Robert, Jen-Tsung Chen, and Arumugam Vijaya Anand

3. Marine Bioactive Compounds as Potential Anti-COVID-19 Medications
Varshita Srivastava and Dhaneshwar Prusty

4. Marine Polysaccharides as Broad-Spectrum Drugs Against Coronaviruses
Anand Kumar Pandey and Shalja Verma

5. Anti- SARS-CoV-2 Activity of Marine Terpenoids: The Mode of Action on Protein Targets
Nidhilangelo M. M. and Ranjith Kumavath

6. Anti- SARS-CoV-2 Activity of Marine Bacteria-Derived Compounds: The Mode of Action
Amany A. Thabet and Fadia S. Youssef

7. The Role of Marine Bacteria-Derived Bioactive Compounds in COVID-19 Management
Supti Das, Dwaipayan Sinha, Sukanya Chatterji, Arindam Ganguly, Arpan De, Aqsa Majgaonkar, Zoofishan Kazi, Arun Kumar Maurya, Muhammad Sohail, and Nisha Bhat

8. Anti-SARS-CoV-2 Potential of Marine Fungi-Derived Compounds and Their Roles in Covid-19 Treatment
Eman Shawky and Dina S. Ghallab

9. Algae-Derived Marine Bioactive Compounds Against COVID-19
Saloni Joshi, Aditi Tyagi, Vijeta Prakash, and Reema Gabrani

10. The Potential Role of Marine Seaweeds in the Management of COVID-19
Ravichandran Sneha, Parthiban Akshaya, Esakkimuthu Balaji, Aasivtham Alwin Robert, Shanmugam Velayuthaprabhu, Madhavan Shenbaam, Puzhakkal Abhirami, and Arumugam Vijaya Anand

11. The Role of Marine Sponge-Derived Bioactive Compounds in COVID-19 Management
Arun Bahadur Gurung and Atanu Bhattacharjee

12. Anti-SARS-CoV-2 Bioactive Compounds Derived from Marine Sponges: A Mechanistic Insight into Their Inhibitory on Protein Targets
Badrinarayanan Varalakshmi, Purushothaman Gajalakshmi, Vasudevan Suganya, Thiruvengadam Abarna, Gunasekaran Raveena, Veeramalai Sathya Priya, Chandrashekar Mamtha, Ramasamy Manikandan, Shanmugam Ramya, and Arumugam Vijaya Anand

13. Astaxanthin and Its Effect on SARS-CoV-2
S. Aruna Sharmili, S. Jayashree, K. Sonia, G. Mayakkannan, S. Shruthi, and Sekar Vijayakumar

14. Holyrine A: A Marine Indole-Alkaloid with Promising Pan-Inhibition Activity Against SARS-CoV-2
Rania Hamdy, Imene Lazreg, Yasmina Lashine, Mohamed I. Husseiny, and Sameh S. M. Soliman

15. A Marine Bioactive Compound Fistularin-3 Against SARS-CoV-2 and the Underlying Mechanism
Shivani Pathak, Kalpana Patni, and Neha Garg

16. Potential Role of Marine Bioactive Compounds Against the Main Protease and RNA-Dependent RNA Polymerase of SARS-CoV-2
Kushagra Dubey and Raghvendra Dubey

17. Marine Natural Products with Anti- SARS-CoV-2 Activity in Southeast Asia
Sora Yasri and Viroj Wiwanitkit

Index


About the Authors / Editors:
Editor: Jen-Tsung Chen, PhD
Professor of Cell Biology, Department of Life Sciences, National University of Kaohsiung, Taiwan

Jen-Tsung Chen, PhD, is a Professor of Cell Biology at the National University of Kaohsiung in Taiwan, where he teaches genomics, proteomics, plant physiology, and plant biotechnology. His research interests include bioactive compounds, chromatography techniques, plant molecular biology, plant biotechnology, bioinformatics, and systems pharmacology. He is an active editor of academic books and journals in an effort to advance the exploration of multidisciplinary knowledge involving plant physiology, plant biotechnology, nanotechnology, ethnopharmacology, systems biology, and drug discovery. He serves as an editorial board member and a guest editor for several reputed journals. Dr. Chen has published books in collaboration with international publishers on diverse topics such as drug discovery, herbal medicine, medicinal biotechnology, nanotechnology, bioengineering, plant functional genomics, plant speed breeding, CRISPR-based plant genome editing, and artificial intelligence. Dr. Chen has been included in the list of the World Top 2% Scientists 2023 by Stanford University.




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