Polymer Science

Alginates
Versatile Polymers in Biomedical Applications and Therapeutics

Editors: Md Saquib Hasnain, PhD
Amit Kumar Nayak, PhD

Alginates

Published
Pub Date: April 2019
Hardback Price: see ordering info
Hard ISBN: 9781771887823
Paperback ISBN: 978-1-77463-457-8
E-Book ISBN: 9780429023439
Pages: 646 pp w/index
Binding Type: hardbound / ebook / paperback
Notes: 8 color and 133 b/w illustrations

Now Available in Paperback


This new volume, Alginates: Versatile Polymers in Biomedical Applications and Therapeutics, explores the latest research on the use of alginate as a biopolymer in various biomedical applications and therapeutics. The biomedical and therapeutic uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics.

Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals, as medical diagnostic aids, and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. These include liquid gels, powders, beads, films, tablets, capsules, microspheres, microparticles, nanoparticles, nanosponges, nanofibrils, and nanocomposites. A thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields needs to be thoroughly understood, and this volume offers an abundance of information toward that end.

With chapters from experts in the field, this volume provides insight into the complete alginate chemistry, collection, chemical modifications, characterization, and applications of alginate in the healthcare field. The volume will be of interest to professors, researchers and early career young scientists in the disciplines of medical and pharmaceutical sciences, as well as drug delivery scientists, nanotechnologists and nanobiotechnologists, and scientists working in the disciplines of biomedical engineering and nanomedicine.

CONTENTS:
Preface

1. Alginates: Source, Chemistry, and Properties
Mithilesh Yadav and Younes Ahmadi

2. Recent Advances of Alginates as Material for Biomedical Applications
Milan Milivojevic, Ivana Pajic-Lijakovic, and Branko Bugarski

3. Alginates: Hydrogels, Their Chemistry, and Applications
Verónica Elena Manzano, María Natalia Pacho, Joana Elisa Tasqué, and Norma Beatriz D’Accorso

4. Alginate-Based Hydrogels: Synthesis, Characterization, and Biomedical Applications
Vandana Singh and Angela Singh

5. Chemically Modified Alginates for Advanced Biomedical Applications
Ibrahim M. El-Sherbiny, Mostafa M. Abd Al Aziz, and Esraa A. Abdelsalam

6. Bionanocomposites of Alginates, Their Chemistry, and Applications
Nancy L. García, Mario Contín, Carlos A. Rodriguez Ramirez, and Norma B. D’Accorso

7. Alginate and Its Applications in Tissue Engineering
Dilshad Qureshi, Seemadri Subhadarshini, Suraj Kumar Nayak, Doman Kim, Preetam Sarkar, Indranil Banerjee, and Kunal Pal

8. Alginate-Based Scaffolds in Bone Tissue Engineering Applications
S. Viji Chandran, V. Sanjay and N. Selvamurugan

9. Alginate: Properties, Pharmaceutical, and Tissue Engineering Applications
Joshy K. S., Snigdha S., and Sabu Thomas

10. Alginate: Drug Delivery and Application
Gautam Singhvi, Rapalli Vamshi Krishna, Kowthavarapu V. Krishna, and Sunil Kumar Dubey

11. Chemical and Physical Modifications of Alginate to Improve Its Use as Carriers in Delivery Systems
Gabriela Valladares, Karina Bierbrauer, and Miriam Strumia

12. Updates on Alginate-Based Interpenetrating Polymer Networks for Sustained Drug Release
Ibrahim M. El-Sherbiny and Kholoud Arafa

13. Alginate Nanoparticles
Isra Dmour and Mutasem Taha

14. Alginate-Based Nanocarriers, Modern Therapeutics
Vandana Singh and Angela Singh

15. Alginate-Based Composites in Drug Delivery Application
Ankita Tiwari, Ankit Jain, Amit Verma, Pritish Panda, and Sanjay K. Jain

16. Hydroxyapatite-Alginate Composites in Drug Delivery
Sitansu Sekhar Nanda, Dong Kee Yi, M Saquib Hasnain, and Amit Kumar Nayak

17. Alginate-Based Gastro-Intestinal Tract Drug Delivery Systems
Sougata Jana, Kalyan Kumar Sen, and Sabyasachi Maiti

18. Alginate Hydrogels as Colon-Targeted Drug Delivery System
Pramendra Kumar and Deepak Kumar

19. Alginate Carriers for Treatment of Ocular Diseases
Ravi Sheshala and Tin Wui Wong

20. Alginate Carriers for Bioactive Substances: Herbal Natural Compounds and Nucleic Acid Materials
Maria Rosaria Lauro, Giovanni Amato, Francesca Sansone, Claudia Carbone, and Giovanni Puglisi

Index


About the Authors / Editors:
Editors: Md Saquib Hasnain, PhD
Shri Venkateshwara University, Gajraula, Amroha, U.P, India

Md Saquib Hasnain, PhD, has over six years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially in systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches as well as development and characterization of polymeric composites, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, HPLC, LC-MS, and many more. He has authored over 30 publications in various high-impact peer-reviewed journals, 30 book chapters, and one Indian patent application to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (H-Index: 12). He has also participated and presented his research work at over ten conferences in India and abroad. He is also a member of several scientific societies, including the Royal Society of Chemistry, Great Britain; International Association of Environmental and Analytical Chemistry, Switzerland; and Swiss Chemical Society, Switzerland.

Amit Kumar Nayak, PhD
Associate Professor, Seemanta Institute of Pharmaceutical Sciences, Odisha, India

Amit Kumar Nayak, PhD, is currently an Associate Professor at the Seemanta Institute of Pharmaceutical Sciences, Odisha, India. He has over ten years of research experience in the field of pharmaceutics, especially in the development and characterization of polymeric composites, hydrogels, novel and nanostructured drug delivery systems, formulation characterization using FTIR, DSC, PXRD, SEM, TEM, and HPLC. He has authored over 120 publications in various high-impact peer-reviewed journals and has 34 book chapters to his credit. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (H-Index: 28, i10-Index: 68). He has been the permanent reviewer of many international journals. He also has participated and presented his research work at several conferences in India and is a life member of the Association of Pharmaceutical Teachers of India (APTI). He has earned his PhD in Pharmaceutical Sciences from IIFTM University, Moradabad, U.P., India.




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