Medicine & Health Sciences

Advanced Studies in Experimental and Clinical Medicine
Modern Trends and Latest Approaches

Editors: P. Mereena Luke
K. R. Dhanya, PhD
Didier Rouxel, PhD
Nandakumar Kalarikkal, PhD
Sabu Thomas, DSc

Advanced Studies in Experimental and Clinical Medicine

Published. Available now.
Pub Date: March 2021
Hardback Price: see ordering info
Hard ISBN: 9781771889063
E-Book ISBN: 9781003057451
Pages: 310pp w/ index
Binding Type: Hardback
Notes: 8 color and 51 b/w illustrations

This volume, Advanced Studies in Experimental and Clinical Medicine: Modern Trends and Latest Approaches, provides a selection of chapters on new developments in various areas of clinical medicine, including dental, surgery, and general practice. These scientific papers and chapters analyze the diagnostic processes and inform of new and novel diagnostic techniques.

This book is divided into two sections; the first section contains review papers and includes an overview of experimental and clinical medicine, explaining its history from ancient medicine to modern medicine. The second section presents a selection of original research papers from respected authors on a variety of topics.

This book is recommended to immunologists, physiologists, and medical practitioners.

CONTENTS:
Preface

SECTION I
1. Developments of Health Care: A Brief History of Medicine
P. Mereena Luke, K. R. Dhanya, Jozef T. Haponiuk, Didier Rouxel, and S. Thomas

2. Immunomodulatory Effect of Plant-Based Extracts on Neurodegeneration
Koel Sinha and Chitrangada Das Mukhopadhyay

3. Bio-Implants Derived from Biocompatible and Biodegradable Biopolymeric Materials
Neetha John

4. Versatile Nature of Poly(Vinylpyrrolidone) in Clinical Medicine
K. R. Dhanya, Mereena Luke, Sabu Thomas, Dider Rouxel, and Nandakumar Kalarikkal

5. Heat Shock Protein 90 (Hsp90) Inhibitory Potentials of Some Chalcone Compounds as Novel Anti-Proliferative Candidates
Debarshi Kar Mahapatra, Sayan Dutta Gupta, Sanjay Kumar Bharti, Tomy Muringayil Joseph, and Józef T. Haponiuk

6. Perspectives of Cashew Nut Shell Liquid (CNSL) in a Pharmacotherapeutic Context
Tomy Muringayil Joseph, Debarshi Kar Mahapatra, Jozef Thadevoos Haponiuk, and Sabu Thomas

7. Role of Tandem Mass Spectrometry in Diagnosis and Management of Inborn Errors of Metabolism
Kannan Vaidyanathan and Sandhya Gopalakrishnan

SECTION II
8. Elevated Cytosolic Phospholipase A2?as a Target for Treatment and Prevention the Progression of Neurodegenerative Diseases
Rachel Levy, YuliaSolomonov, Kesenia Kasianov, Yafa Malada- Edelstein, and Nurit Hadad

9. Real-Time Biospeckle Monitoring of Drug Action in Trypanosoma cruzi Parasites
Mohammad Zaheer Ansari, Hilda C. Grassi, Humberto Cabrera, Ana Velásquez, Efrén D. J. Andrades, and A. Mujeeb

10. Hirakbhasma: A Potential Ayurvedic Antibacterial Drug Assessed by in vitro Pre-Clinical Studies
Sutapa Som Chaudhury, Bhuban Ruidas, Prasanta Kumar Sarkar, and Chitrangada Das Mukhopadhyay

11. Pathophysiology of Fluorosis and Calcium Dose Prediction for Its Reversal in Children: Mathematical Modeling, Analysis, and Simulation of Three Clinical Case Studies
Suja George, A. B. Gupta, Mayan K Mehta, and Akshara Goyal

12. Diagnosis of Mycobacterium tuberculosis from Sputum DNA Using Multiplex PCR
R. Gopinath, Suthandira Munisamy, M. Jeyadevasena, J. M. Jeffrey, and Elanchezhiyan Manickan

13. Anti-HSV and Cytotoxicity Properties of Three Different Nanoparticles Derived from an Indian Medicinal Plants
K. Vasanthi, G. Reena, G. Sathyanarayanan, and Elanchezhiyan Manickan

14. A Positive Correlation between IGg2 Antibody Preponderance and Clearance of HSV during Active HSV Infections
K. Vasanthi, G. Sathya Narayanan, Pugalendhi, and Elanchezhiyan Manickan

15. Effects of Thermal Cycling on Surface Hardness, Diametral Tensile Strength, and Porosity of zn Organically Modified Ceramic (Ormocer) Based Visible Light Cure Dental Restorative Resin
P. P. Lizymol and Sree Chitra

Index


About the Authors / Editors:
Editors: P. Mereena Luke
Research Scholar, Department of Polymer Technology, Chemical Faculty, Gdansk University of Technology, Poland

P. Mereena Luke is a Research Scholar in the Department of Polymer Technology, Chemical Faculty, at Gdansk University of Technology, Poland. She recently completed a two-year project sponsored by the University Grants Commission on “Preparation and Evaluation of Dendrimeric Nano Systems for Drug Delivery Applications” at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, India. She has published articles in international and national professional journals and has also presented her work at different international and national conferences. She has written chapters for several books. Her research interests include dendrimer-based drug delivery, nanomedicine, natural polymers, phytochemistry synthesis, and applications of dendrimer drug complexes for biomedical applications.

K. R. Dhanya, PhD
Postdoctoral Fellow, International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, India

K. R. Dhanya, PhD, is a Postdoctoral Fellow at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, India. She has published articles in professional international and national journals and has presented her work at various international and national conferences as well. She has authored and co-authored several book chapters. Her research interests include polymer synthesis, hydrogels, water purification, polymer-nanocomposites, and photocatalytic degradation.

Didier Rouxel, PhD
Professor, Institut Jean Lamour, Université de Lorraine, France

Didier Rouxel, PhD, is a full professor at the Institut Jean Lamour, Université de Lorraine, France. His current research areas include elastic properties of polymeric materials studied by Brillouin spectroscopy, development of polymer-nanoparticle nanocomposite materials, development of micro-devices based on electro-active polymers, piezoelectric nanocrystals, and microsensor development for surgery. He has over 100 publications to his name, including over 60 in international journals, plus book chapters, invited conference presentations, seminars, and other communications. He is a member of the French Society of Nanomedicine; the PhD thesis director of the C’Nano Thesis National Prize 2013 (category Interdisciplinary Research) (Van Son Nguyen, “Development of P (VDF-TrFE); and Nanocrystal Hybrid Nanocomposite Films and Integration into Micro-Structured Devices” from the University of Lorraine, 2012); and thesis director of the winner of the French-Indian Scholarship Raman-Charpak 2015 (Camille Thevenot, “Modulation of Elastic Properties of Nanocomposites,” Mahatma Gandhi University, Kottayam University). Dr. Rouxel was awarded the Scientific Excellence Award (PES) in 2013 and is a holder of the doctoral supervision and research bonus (PEDR) 2007–2011.

Nandakumar Kalarikkal, PhD
Director, International and Inter University Centre for Nanoscience and Nanotechnology; Director and Assistant Professor, School of Pure and Applied Physics at Mahatma Gandhi University, Kerala, India

Nandakumar Kalarikkal, PhD, is the Director of the International and Inter University Centre for Nanoscience and Nanotechnology as well as the Director and Assistant Professor in the School of Pure and Applied Physics at Mahatma Gandhi University, Kerala, India. His current research interests include synthesis, characterization, and applications of various nanostructured materials, laser plasma, and phase transitions. He has published more than 160 research articles in peer-reviewed journals and has edited 15 books. He has supervised many PhD, MPhil, and master’s theses. He has four patents to his credit. Very recently, Dr. Nandakumar was honored with “Professor at Lorraine” by the University of Lorraine, France, for his academic excellence. Dr. Nandakumar obtained his master’s degree in physics with a specialization in industrial physics and his PhD in semiconductor physics from Cochin University of Science and Technology, Kerala, India. He was a postdoctoral fellow at NIIST, Trivandrum, and later joined Mahatma Gandhi University, Kerala, India.

Sabu Thomas, DSc
Vice Chancellor, Mahatma Gandhi University; Professor of Polymer Science and Technology and Founding Director of the International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, India

Sabu Thomas, PhD, DSc, FRSC, is the Vice Chancellor of Mahatma Gandhi University, Kottayam, Kerala, India, and Professor of Polymer Science and Engineering at the School of Chemical Sciences as well as Founder Director of the International and Inter University Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University, Kottayam, India. He has supervised many PhD, MPhil, and master’s theses. He has five patents to his credit. He received the coveted Sukumar Maithy Award proclaiming him the best polymer researcher in the country for the year 2008. Professor Thomas received number of awards, including MRSI and CRSI medals; the Dr. APJ Abdul Kalam Award for Scientific Excellence–2016; and the Lifetime Achievement Award from the Indian Nano-Biologists Association for his excellent work. He was the recipient of a Fulbright-Nehru International Education Administrators Award in 2017. He received TRiLA Academician of the year 2018 award. He has over 800 publications to his credit, including over 70 books. He was cited over 35,765 citations and has an H Index- 94 (Google Scholar) and 81 (Scopus), and listed in the one of the most cited researchers in materials science and engineering by Elsevier Scopus Data 2016. Dr. Thomas has been ranked fifth in India as one of the most productive scientists.




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